What is a common side effect of antipsychotic medications in older adults?

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Extrapyramidal symptoms, which include a range of movement disorders, are a well-known side effect of antipsychotic medications, particularly in older adults. These symptoms can manifest as tremors, rigidity, bradykinesia, and tardive dyskinesia. The risk of experiencing these symptoms often increases with age due to a variety of factors, including changes in metabolism and the presence of comorbid conditions that may affect the central nervous system.

Sedation is also commonly associated with antipsychotics, particularly with those that have higher antihistaminergic properties. Older adults might be more susceptible to these sedative effects because they often have a more sensitive response to medications. This sedation can lead to increased fall risk and complications in this population, making it a significant concern.

While weight gain and increased appetite can be side effects of some antipsychotic medications, they are not exclusive to older adults nor are they as universally common as extrapyramidal symptoms. Additionally, a lower heart rate is not typically classified as a side effect of antipsychotics. Thus, extrapyramidal symptoms or sedation stands out as a particularly relevant concern in geriatric patients undergoing treatment with these medications.

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